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“International clinical trial demonstrates improved survival with new treatment for patients with advanced gastro-oesophageal cancer.” Results presented today at the 2023 ASCO Gastrointestinal Cancers Symposium (ASCO GI)
Approximately 4.4% of global greenhouse gas emissions are caused by healthcare. With the increasingly urgent need for the world to decarbonise if it is to meet its 1.5-2C warming targets, healthcare must play its role. 56 countries have now formally committed to developing low-carbon health systems, with 21 of these committing to net-zero between 2030 and 2050.
New research finds the addition of a common blood pressure treatment does not improve outcomes in patients hospitalised with mild COVID-19.
Dr Kristy Robledo, Research Fellow in biostatistics at the NHMRC Clinical Trials Centre has been announced as the finalist for Woman in STEM Award as part of the Western Sydney Women Awards 2022.
Precision medicine technologies have the potential to revolutionise the way melanoma is detected and managed. This perspective article, outlines the current challenges and potential recommendations for Australian HTA agencies such as the Medical Services Advisory Committee (MSAC) and the Pharmaceutical Benefits Advisory Committee (PBAC) to assess the value of precision medicine diagnostics.
Statin therapies are not the cause of muscle pain in over 90% of those who experience symptoms, according to a new study led by researchers from the Cholesterol Treatment Trialists’ Collaboration.
ABC Radio host Andrea Webb interviews CTC Director of Neonatal Research Professor William Tarnow-Mordi about the human lifeline - the umbilical cord. William discusses recent research that demonstrates delaying cord clamping is highly beneficial.
Doctors determining a person's eligibility for voluntary assisted dying must assess life expectancy which is an 'inherently uncertain and imprecise' task made more difficult by inconsistent wording across state legislation, according to University of Sydney experts.
Some women who undergo preventative surgery to avoid reproductive cancers go on to develop incurable abdominal cancer. A clinical trial, involving the NHMRC Clinical Trials Centre, is testing a way to possibly prevent this.
To recognise International Clinical Trials Day on 20 May, the University of Sydney spoke with Director of the NHMRC Clinical Trials Centre, Professor Meg Jardine, on current research occurring at the CTC and how COVID-19 emphasised the importance of clinical trials.
Professor Alicia Jenkins is the 2022 recipient of the RACP International Medal for her outstanding service in developing countries.
Quality-of-life data from the ENZAMET trial showed greater initial declines in some areas with enzalutamide compared with physician's choice of bicalutamide, nilutamide, or flutamide, in men with recently diagnosed, metastatic hormone-sensitive prostate cancer, but there were overall benefits out to 3 years due to delayed disease progression.
The theme for this year’s Kidney Health Day is “Bridge the Knowledge Gap to Better Kidney Care”. Kidney disease related mortality continues to increase yearly and is projected to be the 5th leading cause of death by 2040. To recognise this important day, we spoke with CTC’s Dr Brendan Smyth and Dr Jessica Dawson who share a passion for improving health outcomes for people with kidney disease.
Prof Meg Jardine and Prof Rachael Morton, Director and Deputy Director of the NHMRC Clinical Trials Centre (CTC) at the University of Sydney joined the world’s leading experts in kidney health at the ISN World Congress of Nephrology (WCN’22) in late February.
The CTC’s Prof Angela Webster has received the HSRAANZ Distinguished Investigator (mid-career) Award for her significant and lasting contribution to the field of health services and health policy research.
New research finds women experience a greater loss in life expectancy, and higher likelihood of premature death from kidney disease than men, highlighting a need to find the cause.
The theme for this year’s World Diabetes Day and for the next 2-years is ‘Access to Diabetes Care’. One hundred years after its discovery, insulin and other diabetes medicines and care still remain beyond the reach of many who need them.
Australian researchers have been awarded a $5 million National Health and Medical Research Council (NHMRC) Synergy Grant for a project that will advance knowledge of the gut, microbiomes, metabolites and diet, and their role in both causing and potentially treating inflammatory respiratory diseases, particularly chronic obstructive pulmonary disease (COPD).
Three CTC researchers have received over $4 million from the National Health and Medical Research Council (NHMRC) to improve the health of Australians.
A common blood pressure medication is at the centre of a new COVID-19 treatment clinical trial led by a collaboration of the NHMRC Clinical Trials Centre at the University of Sydney and The George Institute for Global Health (India, Australia, and the UK).
Researchers are calling for improved national coordination of Australian COVID-19 trials, after analysis finds lack of data sharing and collaboration resulting in crucial research gaps.
HRI’s Professor Ben Freedman, Dr Nicole Lowres and Dr Katrina Giskes have received a significant Medical Research Future Fund (MRFF) grant that is poised to transform Australia’s stroke-related healthcare. The trials will be coordinated by the NHMRC Clinical Trials Centre at The University of Sydney under the guidance of Professors Anthony Keech and John Simes.
A significant international study in cervical cancer treatment, the ANZGOG-led OUTBACK trial will be presented at the 2021 ASCO Annual Meeting Plenary Session to reveal its highly anticipated results.
Sydney researchers are testing whether an existing medication could be repurposed to treat sarcoma.
New study to influence clinical practice globally Changing how pre-term babies' umbilical cords are clamped could improve outcomes and save babies lives, prompting an update of the international guidelines that inform global practice.
The CLARITY 2.0 study looks at the Dimerix lead candidate DMX-200 combined with Angiotensin Receptor Blockers to treat respiratory issues associated with COVID-19. The study will recruit patients at an early stage of respiratory complications, prior to the onset of Acute Respiratory Distress Syndrome (ARDS).
ENZAMET scooped the pool at the ACTA Trial of the Year Awards Ceremony winning the 2020 ACTA Trial of the Year Award, the ACTA STInG Award for Excellence in Trial Statistics and the Consumer Involvement Award. A fantastic achievement and the first trial to win all three awards!
Australian medical research is at risk of punching below its weight unless more attention is paid to the discipline of biostatistics.
The CTC’s Prof Martin Stockler has received the prestigious MOGA Novartis Cancer Achievement Award for his outstanding contribution to medical oncology in Australia.
A new trial being undertaken by the NHMRC Clinical Trials Centre is photographing the back of the eye of those living with diabetes to help them avoid losing their vision and the risks of amputation and heart disease.
Statin therapy is safe and effective in older people over 75 years and reduces major cardiovascular events such as heart attacks and strokes, according to new research by the University of Sydney's Clinical Trials Centre published in The Lancet.