Trial results

Cancer trials

Trial

Description

Lay summary

Trial page

Advanced GIST (62005)

High-dose versus standard-dose imatinib for gastrointestinal stromal tumours

Summary

Info page

Adjuvant GIST (62024) 

Imatinib after surgery for gastrointestinal stromal tumours

Summary

 

ALaCaRT

Australasian Laparoscopic Cancer of the Rectum trial (laparoscopic or open surgery for rectal cancer)

Summary

Info page

ATTACHE

Chemotherapy for secondary bowel cancer in the liver 

Summary

Info page

ATTAX3

Panitumumab added to chemotherapy for oesophagogastric cancer (upper digestive tract)

Summary

 

CABARET

Carboplatin and bevacizumab in recurrent glioblastoma (brain cancer)

Summary

Info page

CannabisCINV

Medicinal cannabis to prevent chemotherapy-induced nausea and vomiting (CINV): Results of the pilot phase of the study

Summary

Info page

CO.17

Cetuximab (Erbutix), for people with advanced bowel cancer

Summary

 

CO.23

Napabucasin (BBI608) for colorectal cancer

Summary

Info page

DREAM

Durvalumab with first-line chemotherapy in previously untreated malignant pleural mesothelioma (DREAM)

Summary

Results published in The Lancet Oncology

Info page

GAP

Chemotherapy before surgery for pancreas cancer

Summary

Info page

ICECREAM 

Antibody treatment for colorectal cancer with a G13D mutation

Summary

Info page

INTEGRATE 

Regorafenib for advanced oesophagogastric cancer (upper digestive tract)

Summary

Info page

NITRO 

Chemotherapy and nitroglycerin for lung cancer

Summary

 

PARAGON 

Anti-oestrogen treatment for chemotherapy-resistant ovarian cancer

Summary

Info page

SCOT 

3 versus 6 months of chemotherapy for bowel cancer

Summary

Info page

SNAC 

Sentinel Node Biopsy versus Axillary Clearance (breast cancer)

Summary

Info page

TACTIC 

Panitumumab for biliary tract cancer (bile duct)

Summary

Info page

TOPGEAR 

Radiation added to chemotherapy for stomach cancer

 

Summary

Info page

Cardiovascular trials

INSPIRE 

Aspirin for the prevention of recurrent venous thromboembolism (meta-analysis of ASPIRE and WARFASA trials)

Summary

 

Diabetes trials

T4DM

Effect of testosterone treatment on type 2 diabetes incidence in high risk men enrolled in a lifestyle program

Summary

Info page

Neonatal and Perinatal trials

APTS 

Australian Placental Transfusion Study (for parents)

Summary

Info page

APTS Echo

Australian Placental Transfusion Study (effects of delayed cord clamping on early blood flow)

Summary

 

BOOSTII

Benefits of oxygen saturation targeting, trial 2

Summary