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The Australian New Zealand Clinical Trials Registry (ANZCTR) is an online public registry of clinical trials based at the CTC. It has been housed and managed by the CTC since 2005.
The ANZCTR accepts trials for registration from all countries, across all therapy areas and all types of health interventions (including pharmaceuticals, surgical procedures, preventive measures, lifestyle, medical devices, treatment and rehabilitation strategies and complementary therapies).
To register a trial, head to www.anzctr.org.au.
The ANZCTR is currently funded by the Australian Department of Health, as well as the Australian Government's National Collaborative Research Infrastructure Strategy program, which is administered via Therapeutic Innovation Australia. This makes it possible for Australian researchers to contribute to a worldwide initiative to make public the details of all clinical trials.
Network and certification
The ANZCTR contributes data to the International Clinical Trials Registry Platform (ICTRP), which was developed by the World Health Organization (WHO). The ANZCTR is a participating registry within the World Health Organization Registry Network, and it meets the requirements of the International Committee of Medical Journal Editors (ICMJE). ANZCTR data is also exported to the consumer-friendly Australian Clinical Trials website, as well as the Australian Cancer Trials website, which helps people search for cancer clinical trials recruiting in Australia, provides information about clinical trials and assists with doctor-patient communication about trials.
Prospective Trial Registration
Prospective trial registration is when key details about a planned clinical trial are made available on a publicly accessible database before enrolment of the first trial participant. These databases are known as clinical trial registries. This facilitates research transparency and helps to reduce publication bias, ensuring that healthcare decisions can be informed by all of the available evidence.
Global backing of registries
The process of prospective trial registration is now widely accepted as an essential part of an overall strategy for improving health outcomes. In 2004 the ICMJE declared that they would not consider a trial for publication without evidence that it had been registered in a publicly accessible trial registry prior to enrolment of the first participant. The Declaration of Helsinki now also explicitly states that ‘every clinical trial must be registered in a publicly accessible database before recruitment of the first subject’ and WHO considers the registration of all interventional trials to be ‘a scientific, ethical and moral responsibility’. In Australia, the National Statement on Ethical Conduct in Human Research has been updated to require prospective registration of clinical trials.