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People based (clinical) studies can guide health outcome prediction and monitoring and can point to but not discern mechanisms of tissue damage or protection. Studies in cultured cells, tissues or animal models can be used to explore mechanisms and to test new treatments. The team and their colleagues conduct diabetes related studies in cells and in animals to elucidate mechanisms of diabetes related tissue damage and protection.
Projects currently undertaken in this area include, Diabetic Retinopathy, Wound Healing, Effects of Metformin on Cardiac Function in Type 1 Diabetes and A Novel Mouse Model of Increased Oxidative Stress.