iCOMP is a systematic review and network meta-analysis with individual participant data on Cord Management at Preterm Birth. The iCOMP Collaboration brings together researchers from all over the world to combine their trial data to:

1. determine the optimal umbilical cord management strategy at preterm birth
2. evaluate the comparative effects of cord management strategies such as milking or delayed cord clamping on neonatal mortality and morbidity
3. investigate the impact of alternative cord management strategies for different key subgroups of infants, such as those requiring resuscitation at birth or born very early (before 32 weeks gestation).

 

Collaborators:

The Collaboration is being led by researchers at the NHMRC Clinical Trials Centre and the Nottingham Clinical Trials Unit. For a complete list of all Collaborators, please see the iCOMP website.

Funded by:

NHMRC Project Grant (GNT1163585),

UK National Institute of Health Research (RPPG060910107)

Chief Investigators:

Anna Lene Seidler, Lisa Askie, Lelia Duley & Alan Montgomery

PROSPERO (International Prospective Register of Systematic Reviews) no.:

CRD42019136640

Contact email:

ctc.icomp@sydney.edu.au

CTC staff involved:

Secretariat: Anna Lene Seidler (Chair), Kylie Hunter, Angie Barba, Sol Libesman, Mason Aberoumand, Jonathan Williams (data & project management)

Advisor: John Simes

Trial representatives: William Tarnow-Mordi, Kristy Robledo

Publications:

Seidler AL, et al. on behalf of the iCOMP Collaboration. Systematic review and network meta-analysis with individual participant data on Cord Management at Preterm Birth (iCOMP): study protocol. BMJ Open 2020;10:e034595. doi: 10.1136/bmjopen-2019-034595