Trial Summary:

SAFER-AUS aims to determine if offering screening for AF (including paroxysmal AF) to people aged 70 and over leads to reduced incidence of stroke compared to usual care and what impact it has on other key outcomes (both harm and benefit). It is the only international arm of the SAFER study from the University of Cambridge funded by NIHR. The combined trial will be the largest RCT in the world, and the UK part had already randomised over 35,000 patients. SAFER includes an internal pilot phase which will be used to determine whether the trial is likely to answer the research question on the basis of early findings.

Supported By:

Medicine Research Future Fund international Clinical Trial Collaboration (MRFF ICTC) grant


Patients in GP practices aged 70 years or older who are not on long-term anticoagulation therapy, or on a palliative care register or residing in a nursing/care/residential home.

Registration ID:





Start Up

Activation Date:



Professor Ben Freedman (Chief Investigator)