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A Phase 2 trial of durvalumab (MEDI4736) and tremelimumab with chemotherapy in metastatic EGFR mutant non-squamous non-small cell lung cancer (NSCLC) following progression on EGFR Tyrosine Kinase Inhibitors (TKIs) (ILLUMINATE)
See ANZCTR for full trial details >
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Trial Summary: |
To evaluate the efficacy and tolerability of dual blockade combination durvalumab and tremelimumab with platinum-pemetrexed in patients with metastatic NSCLC (T790+ve or T790M-ve) who progressed on EGFR- Tyrosine Kinase Inhibitors. |
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Supported By: |
AstraZeneca |
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Eligibility: |
Adults with relapsed non-squamous NSCLC with EGFR mutation with or without T790M mutation. |
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Registration ID: |
ACTRN12618001742268 |
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Participation: |
Australia & Taiwan |
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Status: |
Closed |
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Activation Date: |
Q1 2019 |
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Chairs: |
A/Prof Chee Lee (St George Hospital) |
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Contact: |