CRESTONE is a multicenter open-label, phase 2 trial of seribantumab in patients with NRG1 gene fusion-positive, advanced solid tumours. The Australian patient subset, known as MoST CRESTONE, will be identified through the MoST program.

 

Trial Summary:

To assess the clinical activity of seribantumab in patients with NRG1 fusion positive locally advanced or metastatic solid tumours.

Supported By:

Elevation Oncology Inc.

Eligibility:

Adults with recurrent, locally advanced or metastatic solid tumours which harbour the NRG1 gene fusion and have had received prior standard treatment.

Registration ID:

NCT04383210

Participation:

USA, Canada, Australia

Australian Lead Group:

N/A

Status:

Closed

Activation Date:

20 November 2021

Chairs:

Dr Subotheni Thavaneswaran

Contact:

mostcrestone.study@sydney.edu.au