Trial results

Cancer trials

Trial

Description

Lay summary

Trial page

Articles

ACED

Phase II randomised placebo-controlled double-blind study of acetazolamide versus placebo for cerebral oedema in recurrent and/or progressive high-grade glioma requiring treatment with dexamethasone

Summary

Info page

 

Advanced GIST (62005)

High-dose versus standard-dose imatinib for gastrointestinal stromal tumours

Summary

Info page

 

Adjuvant GIST (62024) 

Imatinib after surgery for gastrointestinal stromal tumours

Summary

 

 

ALaCaRT

Australasian Laparoscopic Cancer of the Rectum trial (laparoscopic or open surgery for rectal cancer)

Summary

Info page

 

APTS

Placental transfusion at birth

Summary

Info page

 

ATTACHE

Chemotherapy for secondary bowel cancer in the liver 

Summary

Info page

 

ATTAX3

Panitumumab added to chemotherapy for oesophagogastric cancer (upper digestive tract)

Summary

 

 

CABARET

Carboplatin and bevacizumab in recurrent glioblastoma (brain cancer)

Summary

Info page

 

CannabisCINV

Medicinal cannabis to prevent chemotherapy-induced nausea and vomiting (CINV): Results of the pilot phase of the study

Summary

 

Info page

Annals of Oncology - paper

Annals of Oncology - editorial

CO.17

Cetuximab (Erbutix), for people with advanced bowel cancer

Summary

 

 

CO.23

Napabucasin (BBI608) for colorectal cancer

Summary

Info page

 

DREAM

Durvalumab with first-line chemotherapy in previously untreated malignant pleural mesothelioma (DREAM)

Summary

Info page

Results published in The Lancet Oncology

GAP

Chemotherapy before surgery for pancreas cancer

Summary

Info page

 

ICECREAM 

Antibody treatment for colorectal cancer with a G13D mutation

Summary

Info page

 

INTEGRATE 

Regorafenib for advanced oesophagogastric cancer (upper digestive tract)

Summary

Info page

 

LUMOS

Low and Intermediate Grade Glioma Umbrella Study of Molecular Guided
TherapieS at relapse

Summary

Info page

BMJ Open Protocol Publication

NITRO 

Chemotherapy and nitroglycerin for lung cancer

Summary

 

 

PARAGON 

Anti-oestrogen treatment for chemotherapy-resistant ovarian cancer

Summary

Info page

 

SCOT 

3 versus 6 months of chemotherapy for bowel cancer

Summary

Info page

 

SNAC 

Sentinel Node Biopsy versus Axillary Clearance (breast cancer)

Summary

Info page

 

TACTIC 

Panitumumab for biliary tract cancer (bile duct)

Summary

Info page

 

TOPGEAR 

Radiation added to chemotherapy for stomach cancer

 

Summary

Info page

 

VERTU

A randomized phase II trial of veliparib, radiotherapy, and temozolomide in patients with unmethylated MGMT glioblastoma

Summary

Info page

Neuro-Oncology publication

Cardiovascular trials

INSPIRE 

Aspirin for the prevention of recurrent venous thromboembolism (meta-analysis of ASPIRE and WARFASA trials)

Summary

 

Diabetes trials

T4DM

Effect of testosterone treatment on type 2 diabetes incidence in high risk men enrolled in a lifestyle program

Summary

Info page

Neonatal and Perinatal trials

APTS 

Australian Placental Transfusion Study (for parents)

Summary

Info page

APTS Echo

Australian Placental Transfusion Study (effects of delayed cord clamping on early blood flow)

Summary

 

BOOSTII

Benefits of oxygen saturation targeting, trial 2

Summary