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OUR IMPACT
Pravastatin treatment for six years was found to reduce death from cardiovascular disease by 24%, and overall mortality by 23%. Long-term follow-up has shown that this improved survival rate continues for almost two decades, largely due to the prevention of cardiovascular deaths. This represents an absolute reduction of 3% in mortality (i.e. 33 patients needed to be treated with pravastatin over 6 years to save one life).
The results of LIPID impacted upon cholesterol treatment guidelines worldwide.
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ABOUT LIPID |
The LIPID study was the first trial in the world to examine the effects of statins on coronary mortality in patients with a previous acute coronary syndrome and a broad range of cholesterol levels at baseline, reflecting patients seen in usual clinical settings. The LIPID team comprised of Australian and New Zealand physicians and research coordinators from a total 87 hospitals. The study was funded by Bristol Myers Squibb, supported by the National Heart Foundation of Australia, and coordinated by the NHMRC Clinical Trials Centre, University of Sydney. The study proved the statin-lowering approach significantly increased the chances of study participants living a longer life with fewer heart attacks, strokes and other cardiovascular events. LIPID has changed clinical practices worldwide, and after 20 years, LIPID is still answering questions about atherosclerotic vascular diseases. |
FAST FACTS |
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DURATION |
1990 - 1992 |
COLLABORATORS |
The study was funded by Bristol Myers Squibb, supported by the National Heart Foundation of Australia, and coordinated by the NHMRC Clinical Trials Centre, University of Sydney. |
FURTHER READING |
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