Preoperative chemoradiotherapy and postoperative chemotherapy with capecitabine and oxaliplatin compared with capecitabine alone in locally advanced rectal cancer.

 

Trial Summary:

The PETACC6 study is an EORTC-led open-label, randomised, multinational two-arm phase III study investigating whether the addition of oxaliplatin to preoperative fluoropyrimidine-based chemoradiation and postoperative fluoropyrimidine-based chemotherapy improves disease-free survival in locally advanced rectal cancer.

Supported By:

Cancer Australia; Cancer Council NSW

Eligibility:

Patients with locally advanced rectal cancer

Registration ID:

ACTRN12608000403336

Participation:

International

Australian Lead Group:

AGITG

Status:

closed

Activation Date:

22/04/2009

Chairs:

Hans-Joachim Schmoll (international), Tim Price (Australia)

Contact:

petacc6.study@sydney.edu.au